Rome, RM, Italy · ISCB
CASP17, the 17th Critical Assessment of Structure Prediction, will be held in Rome, Italy, December 1–5, 2026, and will bring together the international structural biology and computational modeling community for a close look at what today’s prediction methods can actually do. Centered on the results of the latest blind CASP experiment, the meeting will feature independent assessments, presentations from leading prediction groups, discussion sessions, posters, and extensive opportunities for informal exchange. Topics will include protein and RNA structure prediction, protein complexes and protein–nucleic acid complexes, immune complexes, ligand binding, and conformational ensembles. Special emphasis is placed on emerging AI-driven approaches. CASP meetings are distinctive because performance is tested prospectively, before experimental structures are publicly available. The result is an unusually clear view of genuine progress, remaining limitations, and the directions in which the field is moving. CASP17 Conference will also explore new ways of broadening community participation in structure prediction challenges, including potential collaboration with platforms such as Kaggle. Early registration ends September 10, 2026. Beginning September 11, registration increases to $1,350 for academic participants and $1,750 for industry participants.